Thursday, October 31, 2019

Nigerias Position on the Palestinian-Israeli Conflict Essay

Nigerias Position on the Palestinian-Israeli Conflict - Essay Example The General Assembly reiterated that it is always illegal to acquire a territory by use of force or any threat and found that Israel has been breaching the international law. The conflict between the two countries has been present for a long time, thus there is a need to settle the situation between the two. Without taking the side of the Palestine, the country supports the call for Israel to respect and honour its responsibilities and obligations in the international community. Nigeria encourages that both country will do everything to make peace in good faith. Palestine should also stop any act of dispute and violence and make peace. The two countries should make compromises to arrive at a suitable peace agreement (UNGA 10/10246). Until today, Nigeria has been very supportive of the Middle East peace process however, the country felt a little frustration regarding the progress of the negotiation. According to Kio Solomon Amieyeofori, the success of the negotiation was up to the con cerned parties, Palestine and Israel. The country still supports the Road Map peace plan as the solution to the continuous conflict of the two countries. The country encourages stopping Israel’s settlement-related activities in East Jerusalem and West Bank and calls to freeze the militant attacks in Gaza.

Tuesday, October 29, 2019

The Vietnam War and its Effect on American Society Essay Example for Free

The Vietnam War and its Effect on American Society Essay The Vietnam War was started by President Eisenhower. He was the first to involve the United States in the conflict between North and South Vietnam, by putting in CIA operatives and military advisors in South Vietnam (ushistory). The USs involvement grew with every passing president. President Kennedy was the first to put soldiers in Vietnam. Johnson orders the first official combat of the United States soldiers. Finally, the war ended after eighteen years after it was declared by President Richard Nixon. The war had a lasting effect on all parties involved. The US lost its first war, the objective of stopping communism from spreading failed. The war was also the first that the people and soldiers couldnt look back on with pride of a sense of accomplishment (Hochgesang, Lawyer, Stevenson 1). Due to the government’s secrecy and over reach of power, a distrust of the United States government, as an institution, grew that still exists today. The fall out of the war had massive, negative impacts on south East Asian countries. More countries would fall to communism. The devastation of the war caused economic repercussions that still effect countries today. Not only did the war cause lasting damage multiple countries, but it allowed situations that caused the death, slaughter, and starvation of millions in the years following the war (sparknotes). The Vietnam War was started based on the Domino Theory. This theory was adopted by President Eisenhower; it concisely stated that if South Vietnam fell to communism, many other South East Asia countries would become more accepting of communism and eventually adopt it (vietnamawbb 1). â€Å"If Indochina falls, Thailand is put in an almost impossible position. The same is true of Malaya with its rubber and tin. The same is true of Indonesia. If this whole part of South East Asia goes under Communist domination or Communist influence, Japan, who trades and must trade with this area in order to exist must inevitably be oriented towards the Communist regime† (vietnamawbb 1) The Domino effect was the driving force for the Vietnam  War. With the end of World War II, the USSR was the greatest threat to Democracy and Capitalism. Vietnam, being in a centralized location, allowed many of the trade routes of South East Asian countries to pass through it. Many traders would have to come into contact with the political and economic structure within Vietnam, and through this eventually communism as a form of government would have to be accepted. The involvement of the United States lead more counties fall to communism. If the United States had not been so reckless with its military investment less countries would have turned to communist governments. The United States was the first domino in the South East Asian countries establishing communistic governments. American leadership viewed communism as an economic and legal philosophy that destroys justice and enslaves men (Nixon 1). This perception, along with the military threats that the communist countries posed at the time, made communism the enemy of freedom and Democracy. The people of the United States had always fought for freedom: The Revolutionary War, The Civil War, World War I, and World War II. Now the world saw the new face of oppression, Communism. That drove the people and the politicians to purposely involve themselves in the Vietnam conflict. The eighteen year war was a complete and utter failure. It cost the American people billions of dollars, almost 60,000 Americans lives and hundred thousands more were injured. The war did not accomplish what it was supposed to do, the objective, stopping communism spreading to South Vietnam, was not achieved. Within two years of the United States ending its military involvement the north took over the south and annexed it forming the Socialist Republic of Vietnam (ushistory 1). In fact, due to the desperate measures that the US took to try and rout the enemy caused, neighboring countries, Laos and Cambodia to fall to Communism. In March of 1969 the United States started a carpet bombing campaign that would last four years. Authorized by President Nixon the operation was kept secret from congress and the American people. Along with the bombing campaign the US also invaded both Laos and Cambodia. The goal of both operations was to disrupt supply lines that aided North Vietnam. In 1973, the carpet bombing campaign became public knowledge and was stopped due to public opinion. This massive bombing displaced almost thirty percent of the populations from both countries,  causing massive instability of the governments there (rabble 1). Through the USs involvement in those countries, communist government were established. Only through the USs bombing campaign and invasion were the communist rebels were able to take over the weakened governments. Another failure and another domino falling because of the United States. A Large Part of the Vietnam War that cause a major change in American society was the discovery and recognition of Post Traumatic Stress Disorder or PTSD and the physical disabilities that many soldiers received during the war. It begins with an event in which the individual is threatened with his or her own death or the destruction of a body part, to such humiliation that their personal identity may be lost.(Hochgesang, Lawyer, Stevenson 1). This is the definition of the traumatic event that causes PTSD. Symptoms include feeling: helplessness, worthlessness, dejection, anger, depression, insomnia, and a tendency to react to tense situations by using survival tactics (Hochgesang, Lawyer, Stevenson 1). PTSD wasnt identified until the 80s (Hochgesang, Lawyer, Stevenson 1). When thousands of Vietnam veterans were reporting the same symptoms. The effects of PTSD usually dont appear until about a year after the traumatic experience, this along with a limited understanding of the human psyche, made it easy for the government to disregard PTSD (Hochgesang, Lawyer, Stevenson 1). The governments disregard for the veterans mental health caused resentment toward the Government, for using them and then not taking care of them after the war. In Vietnam, not only were psychological problems but physical problems like, the massive drug problem among the soldiers. At the start of the war Marijuana was widely used and the soldiers first choice. Then the media found out that drugs were in mass usage in the United States military, the government quickly banned the smoking to marijuana to stop the bad press that came from the drug. Soon after, many soldiers turned to heroin for their fix. This switch was enjoyed by many soldiers because of the different effects of the drugs marijuana slowed down the perception of time, heroin sped up the perception of time. The drugs and alcohol in Vietnam were so inexpensive that they were easily taken to try and forget the horrors that they saw on the battlefield (Hochgesang, Lawyer, Stevenson 1). But with the return of the soldiers to the United States, many had addictions that were exponentially harder to maintain because of the stricter drugs laws in the  US. Most veterans were still too young to buy alcohol in the United States. One of the worst things by far that came from the many publicized addiction employers used serving Vietnam as evidence of a drug addiction, and were refused employment (Hochgesang, Lawyer, Stevenson 1). The movement against the Vietnam War did become widely popularized until 1965 (History 1). Contrary to what many people believe before 1965, there was wide spread support of the war. Only two congressmen voted against president Johnson waging war against north Vietnam (ushistory 1). The student lead protests had the most support during 1968 after a successful North offensive. Over 40,000 men were forced into service each month, through the governments usage of the draft (history 1). This only cause less and less support for the war form the people. The Tet Offensive in January of 1968 was a serious blow to US moral. By February of 1968 only thirty five percent approved of the war and fifty percent actively disapproved of it. Many war veterans joined in the anti-war protest (history 1). As more and more people joined in protest, and more and more information was revealed about the war crimes and horrors that happened in Vietnam, support for the war rapidly decreased until President Nixon announced the end to the USs involvement in the conflict (history 1). The amount of protests that ended in violence and deaths of protesters caused approval of the government to plummet. The United States hiding operations from the American people, like the bombing and invasion of Laos and Cambodia, cause an ingrained distrust of the government in issues like transparences and being morally just that has lasted decades. Over all, the Vietnam war was a failure for United States. The government failed to secure public support of the war after, their promises of a quick war fell short. Not only did they not secure it, they lost support of the American people in the later years of the conlict. The American government made an entire generation of veterans feel like they were tools to be used and thrown away. The Government did not recognize a massive disorder that thousands to veterans got during the war. They lost the trust of generations. The War also cost tens of thousands American lives and destroyed Millions more after the US left the conflict. The wars objective also failed, Vietnam, Laos and Cambodia all established communist government in the years following the war. The Vietnam War was an overall failure and disappointment that still effects people today.

Sunday, October 27, 2019

Molecular Weight Effect of Different Grades of HPC Polymer

Molecular Weight Effect of Different Grades of HPC Polymer Introduction Bioavailability enhancement Wet media milling + spray drying Issues have impact on dissolution performance Novelty of the work Objective Material and methods wet stirred media milling Spray dryer Characterization techniques Results and discussion Physical stability of the milled precursor suspensions Drug breakage kinetics Formation of the NCMPs via spray drying of the precursor drug suspensions Impact of different polymers on the drug dissolution from NCMPs PVP-K30 HPMC-E3 HPC-SSL, HPC-SL, HPC-L Molecular weight effect of different grades of HPC polymer on drug dissolution performance and stability It is estimated that a large percentage of newly developed drug compounds have limited bioavailibity due to their poor water solubility and very slow dissolution rate [1]. According to the Biopharmaceutics Classification System (BCS), class II drugs are categorized as poorly water soluble and highly permeable in human body [2]. To achieve the therapeutic efficacy of these drugs it is very essential to enhance the bioavailability by increasing the solubility or dissolution rate. A number of approaches have been developed over the time to resolve this issue. The reduction of drug particles size to sub-micron or nanometer has been one of the most popular and effective approaches of all [3-6]. By reducing the particles size order of magnitude, specific surface area of the particles increased radically and enhances the rate of absorption and dissolution [7, 8], according to the Noyes-Whitney equation [9]. Drug nanoparticles production technologies are classified into Bottom-up or Top-down or combination of both. The bottom up techniques include precipitation using supercritical fluid, liquid anti-solvent precipitation, and evaporative precipitation, where small drug particles are produced from drug molecules dissolved in organic solvent [10, 11]. In case of top-down approaches, the particles are reduced to the nanometer range [11]. High pressure homogenization [5] and wet media milling [3] are included in top-down approaches. To prepare drug nanosuspension, wet stirred media milling (WSMM) has achieved the most popularity because of its effectiveness, robustness, scalability, high drug loading, and low polymer side effects [5, 12, 13]. Due to many advantages of drug solid dosage form, it is the most popular dosage form to the patients/clinicians. To encounter this high demand, drug nanosuspensions are usually converted into nanocomposite microparticles (NCMPs) using different drying techniques and incorporated into standard solid dosage forms such as tablets and capsules [13, 14]. Vacuum dryer [15, 16], spray-freeze dryer [17, 18], spray dryer [19, 20], and fluidized bed [17] are very prevalent and widely used drying tools in the pharmaceutical industries. Among all the drying techniques, spray drying has already got attention due to its energy intensive, continuous and scalable drying process characteristics and ability to produce micro to nano-sized particles with a very narrow distribution within a very short time frame [21]. Albeit particle size reduction is an effective technique for bioavailability enhancement, stability issue has always been critical for the efficacy of the drug products. In the nanosuspension, drug particles start losing their specific surface area by aggregation due to relatively high surface energy and specific surface area and also for enhanced Brownian motion [22]. For the prevention of aggregation in the wet media and having better stability, polymers and/or surfactants are added to the suspension as stabilizers. These stabilizers provide stability by electrostatic or electrosteric mechanisms [22]. Steric stability provided by the polymer is drug specific. Only few polymers can help to reduce the particle size of a specific drug down to nanometers. Therefore, selecting a proper stabilizer for a specific drug is a very complex process and cannot be generalized easily [23]. Thus, having a better insight about the polymer properties is very crucial to figure out the right stabilize r for a particular drug. Molecular weight of the polymer is a very significant property of polymers, which determines the capability for steric stabilization along with solution properties [24, 25], regulates mechanical property of the films [26], and controls the drug release during oral administration [27]. Consequently, optimum MW and polymer concentration may help to get the best stabilization performance during and after milling, and faster drug release from the composites.   Choi et al. [16] investigated the impact of lower range MW (11,200-49,000 g/mol) of hydroxypropyl cellulose (HW) on itraconazole suspension production and their recovery from the drug composites. In that work, HPC was used solely with the same concentration, and dissolution performance study was absent.   Sepassi et al. [28] studied MW effect of two different polymers hydroxypropylmethyl cellulose (HPMC) and polyvinylpyrrolidone (PVP) on the particle size reduction of milled nabumetone and ha lofantrine suspensions; however, drying and dissolution rate were not studied. Li et al. [29] studied the MW and concentration effect of hydroxypropyl cellulose (HPC) on the dissolution performance of poorly soluble drug griseofulvin (GF) in presence/absence of sodium dodecyl sulfate (SDS) as surfactant. In that investigation, drug nanosuspension was coated and dried on to the surface of pharmatose using fluidized bed technique and also determined the optimum concentration and MW effect of HPC for complete release of the drug particles during dissolution. To authors best knowledge, no comprehensive and systematic study has been performed so far to get the insight about the head to head comparison of different polymers performance and MW effect of the same polymer on the suspension stability after milling and during dissolution of NCMPs produced via spray drying. It is known from prior study that the combined use of polymers and surfactants provide a synergistic effect leading to better stability in the nanosuspension than individual stabilizers [30, 31]. Due to the side effects of surfactant, it is always expected to use minimal amount in the formulation. If only the use of polymer can provide substantial stability in the nanosuspension and immediate release of the drugs in the dissolution from NCMPs, then it is more viable than using surfactant.   Therefore, this study aims to develop an understanding of the polymer MW and different polymer effect on the physical stability of Itraconazole nanosuspension and drug dissolution fr om the composites. Itraconazole (ITZ) suspensions were milled in a WSMM and the nanocomposite particles were produced using a co-current spray dryer. Three different polymers HPC, PVP, and HPMC were used at 4.5% (w/w) concentration to see the polymer effect and for MW effect, three grades (SSL, SL, and L) of HPC having different MW were used. Laser diffraction, SEM, UV- spectroscopy, XRPD, and DSC were used to analyze the drug suspension and composite particles. Dissolution test of the NCMPs were performed by a USP II paddle apparatus. Materials Itraconazole (ITZ), is an antifungal drug with a water solubility 0.13 mg/L (at pH-7 and 25  °C), is a sparingly water soluble drug belong to the BCS Class II was purchased from Jai Radhe Sales (Ahmedabad, India) and was used as-received condition. Three different polymers, hydroxypropyl cellulose (HPC), hydroxypropylmethyl cellulose (HPMC), and polyvinylpyrrolidone (PVP) were used as polymers. Three grades (SSL, SL, and L) of HPC with ~40, ~100, and ~140 kDa molecular weight, respectively, were donated by Nisso America Inc. (New York, NY, USA) and used for steric stabilization. Polymeric stabilizers Methocel E3 grade HPMC and PVP Kollidon 30 were donated by Dow Chemical (Midland, MI, USA) and BASF Corporation (Florham Park, NJ, USA) respectively. Sodium dodecyl sulfate (SDS) is an anionic surfactant used as a wetting agent during dissolution and provide electrostatic stabilization in the suspension, was purchased from Sigma Aldrich (Milwaukee, WI, USA). Zirmil Y grade wear-re sistant yttrium-stabilized zirconia (YSZ) with a median size of 430  µm (400  µm nominal size) was used as the milling media and purchased from Saint Gobain ZirPro (Mountainside, NJ, USA). Methods Wet Stirred Media Milling (WSMM) The presuspension (before milling) was prepared following the same procedure used in Afolabi et al. [32]. All the suspension formulations are tabulated below in Table 1. API (Itraconazole) concentration was kept constant at 10% (w/w) and polymer concentration was 4.5% (w/w) for all the formulation. All the concentrations are reported with respect to deionized water (200g). The formulation with 2.5% (w/w) HPC-SL and 0.2% (w/w) SDS was used as a baseline formulation, because from earlier study it was found to be the optimum for fastest and complete drug release from the composite powders. Prepared drug suspension was milled in a Netzsch wet media mill (Micorcer, Fine Particle Technology LLC, Exton, PA, USA) with 80 ml chamber; 50 ml of the chamber was filled with 400  µm (nominal size) Zirconia beads, which is the milling media and a screen with 200  µm opening was used to hold the beads into the chamber and allowing only the passage of the suspension. A shear mixer (Fisher Scientific Laboratory Stirrer, Catalog No. 14-503, Pittsburgh, PA) was used to prepare the suspension prior to transfer into the holding tank of the miller. The suspension was pumped through a peristaltic pump and was milled under the following conditions: suspension flow rate 126 ml/min, rotor speed 4000 rpm corresponding to a tip speed of 11.7 m/s. To keep the suspension temperature below 35  °C, milling chamber and holding tank both were equipped with a chiller (Advantage Engineering Greenwood, IN, USA).   All the parameters were selected from the earlier work done by Afolabi et al. [31]. To determine the breakage kinetics, particle sizes were measured at different time intervals up to 65 minutes and the suspension were refrigerated at 8  °C for one day before spray drying. Preparation of NCMPs via Spray Drying The prepared nanosuspesions were dried within a day of milling using a spray dryer (4M8-Trix, Procept, Zelzate, Belgium) running in a co-current flow set up. All the operating conditions were taken from Azad et al. [19].The suspensions were atomized at 2 bar atomizing pressure using a bi-fluid nozzle having 0.6 mm tip diameter. In each run, ~120 gm nanosuspensions were sprayed at 1.3-1.6 g/min spray rate using a peristaltic pump (Makeit-EZ, Creates, Zelzate, Belgium). Drying air was fed co-currently from the top of the column at 120  °C temperature and 0.37-0.40 m3/min volumetric flow rate. To avoid sedimentation of the drug particles during spraying, the suspension was stirred using a magnetic stirrer throughout the run. A Cyclone separator was used at 54-70 mbar differential pressure to separate the NCMPs from the outlet air stream and collecting them in a glass jar. The dried powders later on were used for powder sample characterization e.g., XRD, DSC, Rodos, and dissolutio n testing. Particle Size Analysis Particle size distributions of the suspensions were measured at different time interval during milling and after 7-day storage in the refrigerator by laser diffraction (LD) technique using Coulter LS 13 320 (Beckman Coulter, Miami, FL). All the steps involved for measuring PSDs of the suspensions were followed from Li et al. [29]. During sample addition, intensity was maintained between 40-45% while obscuration was below 8%. Mie scattering theory was used to compute the volume-based PSDs in the software. Refractive index value is 1.68 for ITZ and 1.33 for deionized water (medium). Before measuring the PSDs, 2 ml suspension sample was collected from the outlet of the mill chamber and diluted with 5 ml of the respective stabilizer solution using a vortex mixer (Fisher Scientific Digital Vortex Mixer, Catalog no: 0215370, Model No: 945415, Pittsburgh, PA) at 1500 rpm for 1 min. The Particle size distributions (PSDs) of produced NCMPs via spray drying were measured by Rodos/Helos laser diffraction (LD) system (Sympatec, NJ, USA) based on Furnhofer theory with dry powder dispersion module. On the sample chute of the Rodos dispersing system, just about 1 g of the sample was placed. To feed the samples, the sample chute was vibrated at 50% settings and 0.1 bar dispersion pressure was imposed to suck in the falling powder through the sample cell of the laser diffraction system. Determination of Drug Content in the Composite Powders Drug content of the composite powders were measured by assay testing. ITZ solubility is - in dichloromethane (DCM). 100 mg of the NCMPs was dissolved in 20 ml DCM, sonicated for 30 mins to ensure all the ITZ is dissolved in the solvent and then they were allowed to sediment overnight. An aliquot of 100  µl is taken from the supernatant and diluted to 10 ml with DCM. The absorbance of all the samples was measured at 260 nm wavelength via Ultraviolet (UV) spectrophotometer (Agilent, Santa Clara, CA, USA). Six replicates were prepared from each NCMP formulation to calculate mean drug content and percent relative standard deviation (RSD). Scanning Electron Microscopy (SEM) SEM imaging was performed to understand the morphology and particle size of the ITZ particles before and after milling. SEM images of as-received ITZ and baseline formulation was taken using a LEO 1530 SVMP (Carl Zeiss, Inc., Peabody, MA, USA) SEM machine. Approximately, 0.1 ml milled suspension sample was placed on top of a silicon chip (Ted Pella Inc., Redding, CA, USA), and then on top of a carbon specimen holder. The sample was placed into a desiccator for overnight drying. The samples were then sputter coated with carbon before analyzing [33]. X-ray Powder Diffraction (PXRD) The crystallinity of the as-received ITZ, physical mixture of ITZ-excipinets, and spray dried powders were analyzed using PXRD (PANalytical, Westborough, MA, USA), provided with Cu KÃŽÂ ± radiation (ÃŽÂ »= 1.5406 Ã…). The samples were scanned at a rate 0.165 S-1 for 2ÃŽÂ ¸ ranging from 5 to 40 °. Differential Scanning Calorimetry (DSC) DSC of the as-received ITZ, Physical mixture of ITZ-excipients, and spray dried powders was performed using a Mettler-Toledo polymer analyzer (PolyDSC, Columbus, OH, USA). The samples were heated at a rate of 10  °C/min within a range of 25-220  °C under nitrogen gas flow. With the help of the integrated software of the machine, melting temperature Tm and fusion enthalpy ΆHm were determined. Dissolution Testing Dissolution of ITZ from the as-received drug, and spray dried composite powders were determined via a Distek 2100C dissolution tester (North Brunswick, NJ, USA) according to the USP II paddle method.   The dissolution medium was 1000 ml SDS buffer with 3.0 gm/ml concentration at non-sink condition.   The medium was maintained at 37  °C temperature and 50 rpm paddle speed.   The composites were weighed equivalent to a dose of 20 mg of ITZ. Composites were poured into the dissolution medium and manually 4 ml of samples were taken out at 1, 2, 5, 10, 20, 30, and 60 min. Aliquots of the samples were filtered using a 0.1  µm PVDF membrane type syringe filter to avoid any effect of undissolved drug during UV spectroscopy measurement. The absorbance of ITZ dissolved was measured via UV spectroscopy (Agilent, Santa Clara, CA, USA) at 260 nm wavelength. The blank was measured using SDS buffer at the beginning. The amount of drug dissolved was measured using a calibration curve generated from drug concentration vs. absorbance (R2=0.9995 with p Apparent Shear Viscosity of Milled ITZ Suspensions The apparent shear viscosity of the nanosuspension was measured by following the procedure from Afolabi et al. [32], using R/S plus rheometer (Brookfield Engineering, Middleboro, MS, USA). To impart controlled shear rate on the samples from 0 to 1000 1/s in 60 s, a coxial cylinder (CC40) was used. To control the temperature the jacket temperature was kept constant at 25 ±0.5  °C. Drug nanoparticles formation and physical stability of the milled suspensions The formulation of the milled drug (ITZ) suspensions are presented in Table 1. Drug (ITZ) nano suspension was first produced in presence of both steric and an anionic surfactant, SDS (Run 1). Due to the synergistic effect of HPC and SDS [31], Run 1 was used as a baseline to assess the impact of various stabilizers (HPC, HPMC E3, PVP k30, and SDS) in their breakage kinetics and physical stability of the resulting suspensions. This baseline formulation was found to be the optimum formulation from a previous work performed by Meng et al [29]. The molecular weight effect of HPC was then studied in absence of SDS surfactant (Run 2-4) using three different grades of HPC; SSL, SL, and L grades having molecular weight ~40, ~100, and ~140 kDa, respectively. The apparent shear viscosity of all the formulations (Run 1-7) are represented in Figure 1. Formulations with 2.5% (w/w) HPC-SL/SDS, 4.5% (w/w) HPC-SL, and 4.5% (w/w) HPC-L (Run 1, 3, and 4) are showing near Newtonian behavior, indicating the extent of aggregation is very low. Milled drug suspensions stabilized by SDS or polymer alone (except HPC-SL and HPC-L) are showing significant shear-thinning behavior, indicating significant amount of aggregates. References 1.Kesisoglou, F., S. Panmai, and Y. Wu, Nanosizing-oral formulation development and biopharmaceutical evaluation. Advanced drug delivery reviews, 2007. 59(7): p. 631-644. 2.Amidon, G.L., et al., A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharmaceutical research, 1995. 12(3): p. 413-420. 3.Merisko-Liversidge, E. and G.G. Liversidge, Nanosizing for oral and parenteral drug delivery: a perspective on formulating poorly-water soluble compounds using wet media milling technology. Advanced drug delivery reviews, 2011. 63(6): p. 427-440. 4.Panagiotou, T. and R.J. Fisher, Form nanoparticles via controlled crystallization. Chemical Engineering Progress, 2008. 104(10): p. 33-39. 5.Keck, C.M. and R.H. 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Russel, Interactions between colloidal particles and soluble polymers. Advances in Chemical Engineering, 1990. 15: p. 137-228. 26.Rowe, R., The effect of the molecular weight of ethyl cellulose on the drug release properties of mixed films of ethyl cellulose and hydroxypropylmethylcellulose. International journal of pharmaceutics, 1986. 29(1): p. 37-41. 27.Mittal, G., et al., Estradiol loaded PLGA nanoparticles for oral administration: effect of polymer molecular weight and copolymer composition on release behavior in vitro and in vivo. Journal of Controlled Release, 2007. 119(1): p. 77-85. 28.Sepassi, S., et al., Effect of polymer molecular weight on the production of drug nanoparticles. Journal of pharmaceutical sciences, 2007. 96(10): p. 2655-2666. 29.Li, M., N. Lopez, and E. Bilgili, A study of the impact of polymer-surfactant in drug nanoparticle coated pharmatose composites on dissolution performance. Advanced Powder Technology, 2016. 30.Ryde, N.P. and S.B. Ruddy, Solid dose nanoparticulate compositions comprising a synergistic combination of a polymeric surface stabilizer and dioctyl sodium sulfosuccinate. 2002, Google Patents. 31.Bilgili, E. and A. Afolabi, A combined microhydrodynamics-polymer adsorption analysis for elucidation of the roles of stabilizers in wet stirred media milling. International journal of pharmaceutics, 2012. 439(1): p. 193-206. 32.Afolabi, A., O. Akinlabi, and E. Bilgili, Impact of process parameters on the breakage kinetics of poorly water-soluble drugs during wet stirred media milling: a microhydrodynamic view. European Journal of Pharmaceutical Sciences, 2014. 51: p. 75-86. 33.Li, M., et al., An intensified vibratory milling process for enhancing the breakage kinetics during the preparation of drug nanosuspensions. AAPS PharmSciTech, 2016. 17(2): p. 389-399.

Friday, October 25, 2019

All Quite On The Western Front Essay -- essays research papers

â€Å"All Quiet On The Western Front†   Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  World War I was a fierce and very disturbing time for many people. During war people will stretch their own personal boundaries and limits just to stay alive. Although every solider was someone’s son, by the end of the war this was not a factor. By thinking of an enemy as less then human, the act of killing someone’s son was a little easier on the minds of each soldier. To everyday people it is apparent that the war changes people, but the extent of the change is not so easy to see. This change is symbolized in the movie, â€Å"All Quiet On The Western Front.†   Ã‚  Ã‚  Ã‚  Ã‚  At the beginning of the movie, Paul Baumer and his friends were excited about the war. Their teacher Mr. Kantorek, had put a theory in their heads that war was a patriotic duty. If you loved and wanted to support your country, then going to war was a must. With this theory in your head, the act of war is a very difficult thing to handle. Paul realized that war was a horrible place to be. Yes you were fighting for your country, but at the same time all of your friends and family were dying around you. In the end was it really worth it? This was the question that ended up on Paul’s mind, and was a question that would not be soon to leave his conscience.   Ã‚  Ã‚  Ã‚  Ã‚  Paul was a good boy. He had a good education, was a non-smoker, and had many friends. His teacher was amazed a...

Thursday, October 24, 2019

Psyche and Cupid

Relations and origin Though concerning gods and goddesses, Apuleius' Cupid and Psyche was generally relegated to the status of a â€Å"mere† folktale, or in English a fairy tale or in German Marchen. Though a common oral genre found world wide, it is not generally cons William Adlington's idered classical literature. Only with Charles Perrault's Mother Goose Tales and following popularity of other such collections in 17th century did folk tales become recognized in Europe as a legitimate literary genre. Later adaptations English translation of 1566 is excellent reading and for some is still the definitive English translation. In my research, I found some similarities between the modern day story of Beauty and the Beast and the myth of Cupid and Psyche. These similarities, some of which seem rather obvious, can be quite vague also. The myth, as you know tells the tale of a beautiful woman, Psyche and the prophecy of her life as told be the oracle. The story, although seemingly interesting, brings a dismay in my mind because of the lack of it being completely relevant to the story ofCupid and Psyche. As far as characters go, Belle, or Beauty, is compared to Psyche and the beast, although not a beast himself, is parallel to Cupid. The servants in both stories are somewhat the same in the respect that they offer to serve Psyche, or Belle in any way she wishes†¦Ã¢â‚¬ ¦ Long have stories and media been devoted to tales of a beauty ‘taming' a beast, †¦ Psyche and Eros and Beauty and the Beast had similar situations in their †¦ Gender Differences & Similarities are to reconcile the many levels which †¦ he discusses the tension in human consciousness between Eros and Psyche. Both tales take on an animal-husbandry theme of sorts, although in the case of Eros and Psyche, it is the fear of a bestial husband, while in Beauty and the Beast, there is one in actuality. Psyche embraces a husband that she is not allowed to view after having previously been led to believe that she was to be killed and carried off by a demon. When she later tells her sisters of her husban d’s secret identity, out of jealousy they implant ideas in her head that he indeed is this demon that she had been warned about, and encourage her to kill him. She goes on of course to discover that he is not a demon, but the god Eros when she moves to strike him, but at that point her mistrust and curiosity cause him to leave her. Beauty knows of the Beast’s animalistic characteristics and begins fearing him There are many other interesting contrasts. It also leads to Beauty getting her happy ending without all the suffering that Psyche goes on to endure before getting hers. Beauty goes to give her life in exchange for her father's freedom, and Psyche is sent to the mountain that Eros eventually carries her away from after her father is ordered by a god to send her there. Psyche and Beauty are both sent on the road that leads to their â€Å"beasts† in very funeral-like processions. That is, of course, totally different from the cruel suffering that is going to await Psyche. The scene's tone also leads us to anticipate the joy that Beast's transformation will soon bring Beauty, whose happiness will be as great as her momentary depression. Of course, the angst of the scene where Beauty discovers the dying Beast shows us Beauty's true love for him, sharply contrasting Psyche's fearful suspicions. Young, beautiful maidens sent toward their lovers in such a fashion has to be about the theme of lost virginity. Beauty is rewarded with a lavish wedding, the beast taking the form of the prince who resided in her dreams, and a visit from her family for â€Å"having the courage to rescue [the beast] from the terrible enchantment,† (Cole, Page 23); and Psyche was made immortal in reward for fulfilling the horrid tasks that Aphrodite asked of her. In conclusion we see that time and region do not necessarily dictate a change in theme, even if the individual factors within the theme are changed. Psyche and Eros and Beauty and the Beast had similar situations in their stories and dealt with them in quite different ways. Beauty held back her feelings because of appearances, only to discover that the Beast was who she truly wanted all along. Similarly, the beast changing back into a prince does not have the same ring to it as Eros' escape, which he does only after waiting long enough to tell Psyche â€Å"I told you so. Psyche let hers develop too soon by being led by her curiosity, while Beauty delayed accepting the truth (that the man in her dreams was the one before her), until it was almost too late. http://www. megaessays. com/viewpaper/61042. html dop2001 mega essays LLC TITLE:Eros/Psyche vs Beauty/Beast What is the author's purpose for writing Cupid and Psyche? Here is a brief summary of the story.? People started neglecting Venus for the beautiful Psyche so Venus asked her son, Cupid, to make Psyche fall in love with the vilest man on earth, but he would not do it for he had fallen in love with Psyche. The parents of Psyche became worried because their beautiful daughter had not yet been married so they went to ask Apollo for help. He told them to place her on top of a summit alone where someone â€Å"stronger than the gods themselves, would come to her and make her his wife. The parents did so and later when she was asleep she was carried from the summit to a river where she awoke to find a beautiful palace. In the palace she heard voices, her husband, telling her that later on her sisters would be coming and to not let them see him otherwise â€Å"you will bring great sorrow upon me and ruin to yourself† but the next day when her sisters came they became so envious of her good fortune that they worked on a plot to destroy Psyche, telling her to destroy her husband for he was a monster. Later that evening, Psyche went to the bed of her husband, lit a lamp and saw that he was not a monster, but the God of Love and as she bent over his bed some oil from the lamp burned his shoulder, he awoke and fled away bidding his farewell and saying there can not be love where there is no trust. Psyche was determined to find her love so she went to Venus and gave herself as a servant jealous Venus made her do horrible tasks. One of the tasks she had to retrieve beauty from Persephone, but curios Psyche opened the box and fell into a deep sleep. Cupid now healed and still in love with Psyche took away the sleep and asked Zeus to make her immortal so she could be his bride. Zeus did so and Cupid and Psyche were married. 1. Psyche was married to a god, but she herself was mortal, so she was bound by certain rules in her approach to the god ( the superior male). She broke the rules, driven by human desires, and thus hurt his divinity. Here is the conflict between the divine and the profane(human). It is significant fact that the embodiment of the pure mind( psyche) happens to break the rules against the embodiment of love (feeling), and to hurt him. . The ordeals Psyche has to overcome in order to retrieve the love of Cupid (Eros), appear later in many other fairy tales bearing the motive â€Å"In search for the lost husband†. Here the most important one is the symbolic death and rebirth of Psyche, represented by the decent to the kingdom of the dead and her sleep, from which she is awaken by the power of love. She must die as an imperfect human with her human weaknesses to be able to become a true wife of the deity. Note that Psyche is perfect outside, but imperfect inside. The author implies to our human imperfectness and the role of love to overcome it. Eros. The sign position of the Asteroid, Eros, can reveal some of our erotic turn-on, as well as the level of our erotic nature. EROS IN TAURUS Here Eros has little interest in the aggressive ardency of Aries. Taurus is not responsive to getting up at 6 a. m. to do fifty laps at the pool and he would rather not have to compete with anyone to get what he wants. Eros has a different orientation in this sign, namely, an orientation towards pleasure. That means pure and natural, undiluted personal and sensual gratification. This pleasure-seeking eye of the bull is ever on the niceties of sensuality whether they be in the dinning room, on the massage table or in a king size bed. He finds joy in tangible pursuits that revolve around making the body feel good as well as the pleasure of acquisition. Taurus can also become ferociously possessive of those pleasures in an extremely dogmatic way. PSYCHE Psyche Sign describes your characteristics based on the placement of the asteroid Psyche in your natal chart. Along with the sun sign and moon sign, the Psyche sign also helps you understand yourself better. Psyche in Greek means â€Å"Soul†. This has given rise to a most unconventional kind of astrology. The name has come from Greek mythology where the stories are about evil fathers, jealous women and prince charming. Psyche stands for everything related to love, passion, jealousy and our inner self. This asteroid tells us a lot about ourselves and our journey through life. It gives us an aim to know our soul and mind better and know where we stand today. It tells us about what we expect from our partners and what we crave for in a relationship. PSYCHE IN CANCER: Tend to take on nurturing roles, not necessarily with everyone, but definitely with their lover. They will go out of their way to make partner happy. Psyche , What is the theme/moral/message ? Don't let outside influences affect your relationship with another person†¦ or the trust in between you. Cupid and Psyche is a story of love, truth and redemption. For the Greeks its purpose was to emphasize the importance of truthfulness and also to show that redemption can be obtained through hard work and humility. I suppose you could also say there is a lesson in there about the futility of jealousy (like that displayed by Aphrodite and Psyche's sisters), or simply that love can overcome any obstacle. Eros and Psyche is an allegory of the mystical love of the soul (Psyche) for the divine. In some myths Eros was the first God or ‘Protogenoi' from which all creation sprang. The soul (psyche) seeks to return to it's divine source (Eros/God) through mystical love. Psychology actually first started with its original meaning – the study of the soul that is why it is called as psychology. Why? In the early times, philosophers would like to explain why people behave this or that way and since they attribute human behavior with the soul, they try to study the soul instead of behavior. In addition to this, their findings includes that dead people no longer think, work or do anything, Therefore if the person is dead he has no soul. If there is no soul man cannot think and behave the way he is supposed to be and so on ans so forth. This is to give due consideration that in the past the focus of attention is on philosophy (logic specifically) and psychology evolved from it when they found out that it is a different kind of science. http://answers. yahoo. com/search/search_result;_ylt=AkbtFb6mKbWNQjRbX4HxZ1kjzKIX;_ylv=3? eywords_filter=all&p=psyche+and+eros&keywords_search=+Search+Answers Help on ancient Greece love stories 2003 Ramona Bryce Sometimes referred to as Cupid by Roman writers and translators. Interesting Fact: The word â€Å"erotic†, meaning sexual love, comes from the name of Eros. However, even in ancient times, his quality of love was thought to be spiritual as well as physical, and was generally believed to be the deity who caused the love of be auty, healing, freedom, and many other good things as well as the love between people. Children: By Psyche, Volupta or Pleasure; Nyx (Night). With Chaos he is said to have created all birds. Title: fast facts on: Eros url: http://gogreece. about. com/od/greekmythology/a/eros. htm author: deTraci Regula doa: may 8 dop: 2010 Basic Myth: Pan is the god who watches over flocks, forests, mountains, and all wild things. While he is usually despoiling maidens and others, he can also be gentle and is said to have talked Psyche out of commiting suicide over her thwarted love for Eros. Title: Fast facts on: Pan Author: deTraci Regula Doa may 8 Dop: 2010 http://gogreece. about. com/cs/mythology/a/blmythpan. htm Question: What Were the 4 Tasks Psyche Had to Complete? Answer: The taskmaster in the story of Cupid and Psyche was Cupid's mother, the love goddess Venus or Aphrodite. Venus had never liked Psyche, so the opportunity of putting her to a series of tests gave Venus a chance to demand the seemingly impossible. In order for Psyche to win back her husband, Cupid, Venus set 4 seemingly impossible tasks before Psyche: 1. sorting out a huge pile of seeds 2. etrieving the Golden Fleece, 3. filling a flask from the water that fills the River Styx, and 4. returning from the Underworld with a box of the beauty ointment of Proserpina (aka Persephone). Cupid is also known as Amor or Eros, words for love. url: http://ancienthistory. about. com/od/cupidandpsyche/f/Psychestasks. htm Title: Were the 4 Tasks Psyche Had to  Complete? Author: N. S. Gill 2010 Dop:may8 Larger institution:about. com Definition: Psyche is the pe rsonification of the human soul and wife of Eros. Title:Psyche Author: N. S. Gill

Wednesday, October 23, 2019

How Does Stienbeck Explore the Theme of Lonliness in the Novela of Mice and Men

How does John Steinbeck present the theme of loneliness in â€Å"Of Mice and Men†? To be lonely means to feel isolated from others as you may have a lack of friends, family or companionship. In â€Å"Of Mice and Men†, loneliness is a strong theme which is shown by all the characters in one way or another throughout the novel. Even though all the characters in the novel live on the same ranch, they are lonely because of their own personal history and backgrounds, and the only thing that connects them all together is their dreams and aspirations. It can be argued that Curley's wife is the loneliest person in the novel.Curley's wife is portrayed as a very insignificant character. Steinbeck presents this insignificance as she is the only woman on the ranch, and throughout the novel, she is not given a name and only referred to names such as â€Å"Tart†, â€Å"Tramp† and â€Å"Curley's wife† by the other men on the ranch. The name â€Å"Curley's wifeâ⠂¬  shows she is in possession of her husband only and has no importance to anyone else, making her very isolated. She reveals throughout the novel that she is unhappy in her marriage because Curley seems to care little for her, and is really more interested in talking about himself than anything else.In an attempt to make friends, Curley's wife would often attempt to make conversation with the other men on the ranch, by â€Å"looking for Curley† and often asking questions. However, the men on the ranch (particularly Candy) refer to her as a â€Å"tart† who keeps â€Å"giving the eye†, and generally ignore her presence. Further, she stresses her missed ambitions in life; she details twice that she could've been a Hollywood movie star, though the chance was taken from her by her mother, who feared she were too young for show bussiness.This shows that, if she has to become a movie star, she wouldn't have settled for the life she has now, which is miserable and lo nely. Steinbeck presents Curley's wife as a very unfulfilled woman. An almost equally lonely person on the ranch is Crooks – the negro stable buck. Crooks is also a very insignificant character as he is the only black person on the ranch. In the 1930's racism was severe, but they did not know any better than to treat black people in the way they did. Even though

Tuesday, October 22, 2019

NOWAK - Surname Meaning and Origin

NOWAK - Surname Meaning and Origin The Polish surname Nowak means new guy in town, from the Polish root nowy (Czech novà ½), meaning new. The Nowak surname was also occasionally bestowed on one who converted to Christianity (a new man). Nowak is the most common surname in Poland, and is also very common in other Slavic countries, especially the Czech Republic, where Novk tops the list of most common surnames. Novak is also the most common surname in Slovenia, and the sixth most common  surname in Croatia. Nowak was also sometimes Anglicized as Novak, so it can be difficult to count solely on spelling to determine the surnames origins. Surname Origin:  Polish Alternate Surname Spellings: NOVAK, NOWIK, NOVIK, NOVACEK, NOVKOVIC, NOWACZYK   Similar to  NOWAKOWSKI Where do People with the Surname NOWAK Live? According to WorldNames publicprofiler, individuals with the Nowak last name are found in the greatest numbers in Poland, followed by Germany and Austria. The greatest concentration of individuals with the Nowak surname are found in south and central Poland, especially the voivodeships (provinces)  of Wielkopolskie, Swietokrzyskie, Malopolskie, Slaskie and Lubuskie.  The Polish-specific surname distribution map on  moikrewni.pl calculates the population distribution of surnames down to the district level, identifying over 205,000 people with the Nowak surname living in Poland, with the majority found in PoznaÅ„, followed by  Krakà ³w, Warszawa,  Ã… Ãƒ ³dÃ… º,  WrocÅ‚aw, Sosnowiec,  BÄ™dzin and Katowice.   The Novak surname is found in the greatest density in Slovenia, according to Forebears, followed by the Czech Republic, Croatia and Slovakia. It is also about twice as common in the United States as compared to Nowak. Famous People with the Surname NOWAK or NOVAK Bob Novak - American  TV talk show personalityKim Novak - American film actressJan Nowak-JezioraÅ„ski - Polish journalist and WWII hero (he added Nowak as a noms de guerre)Lisa Marie Nowak - former American astronaut Genealogy Resources for the Surname NOWAK Nowak Family Genealogy ForumSearch this popular genealogy forum for the Nowak surname to find others who might be researching your ancestors, or post your own Nowak surname query. FamilySearch - NOWAK GenealogyAccess over 840,000 free historical records and lineage-linked family trees posted for the Nowak surname and its variations on this free genealogy website hosted by the Church of Jesus Christ of Latter-day Saints. DistantCousin.com - NOWAK Genealogy Family HistoryExplore free databases and genealogy links for the last name Nowak. NOWAK Surname Family Mailing ListRootsWeb hosts a free mailing list for researchers of the Nowak surname. They also have one for Novak. Browse or search the archive, or subscribe to submit your own Nowak or Novak query. The Nowak Genealogy and Family Tree PageBrowse genealogy records and links to genealogical and historical records for individuals with the Polish surname Nowak from the website of Genealogy Today. Polish Genealogy Databases OnlineSearch for information on Nowak ancestors in this collection of Polish genealogy databases and indexes from Poland, the United States and other countries. Looking for the meaning of a given name? Check out First Name Meanings Cant find your last name listed? Suggest a surname to be added to the Glossary of Surname Meanings Origins. - References: Surname Meanings Origins Cottle, Basil. Penguin Dictionary of Surnames. Baltimore: Penguin Books, 1967. Menk, Lars. A Dictionary of German Jewish Surnames. Bergenfield, NJ: Avotaynu, 2005. Beider, Alexander. A Dictionary of Jewish Surnames from Galicia.  Bergenfield, NJ:  Avotaynu, 2004. Hanks, Patrick and Flavia Hodges. A Dictionary of Surnames. New York: Oxford University Press, 1989. Hanks, Patrick. Dictionary of American Family Names. New York: Oxford University Press, 2003. Hoffman, William F. Polish Surnames: Origins and Meanings.  Chicago:  Polish Genealogical Society, 1993. Rymut, Kazimierz. Nazwiska Polakow.  Wroclaw: Zaklad Narodowy im. Ossolinskich - Wydawnictwo, 1991. Smith, Elsdon C. American Surnames. Baltimore: Genealogical Publishing Company, 1997. Back to Glossary of Surname Meanings Origins

Sunday, October 20, 2019

Sex Ed and Premarital Sex Essay Example

Sex Ed and Premarital Sex Essay Example Sex Ed and Premarital Sex Essay Sex Ed and Premarital Sex Essay Controversial Speech- Eliza Froemel Should Sex Ed be taught in school? Intro: I remember when I was in 5th grade in Hayward Intermediate School in Mrs. Helander’s class. We learned songs that helped us remember The Preamble of the Constitution, and songs that helped us remember that before a bill became affective it was sent to Capitol Hill to be approved or vetoed. I also remember when we watched a video that had a singing sperm, and a singing egg. I thought it was the funniest thing that was taught in school and couldn’t keep myself from cracking up. But I understood what the video was talking about. I was a kid who, at a young age, was taught by my mother about sex because she got pregnant with me at such a young age she worried, and still does worry, about me following in her footsteps. So my mom had no problem when I came home from school that day and told her what I’d seen at school. Not everyone, though, is as cool with it as my mom was. I: Students who have Sex Education are more likely to have premarital sex. A. In the article Carnal Knowledge: The Sex Ed Debate By Molly Masland, she introduces Tamara Kreinin who is the president of the Sexuality Information and Education Council of the United States. Tamara says, â€Å"Young people are going to learn about sex and our question has to be where do we want them to learn? From the media? From their friends? Or from a educated, responsible adult? † So what Tamara is saying is that younger kids are going to learn about sex regardless of whether or not we teach it in school, so we should teach them in an educational way instead of them learning from unreliable sources such as friends or the media. B. NPR, The Kaiser Family Foundation, and Harvard’s Kennedy School of Gov’t did a survey that showed that only 7 percent of Americans say that sex educations should not be taught in school. For me, that brought up the question, well if only 7 percent of Americans disagree with the teaching of it, why aren’t we teaching it in schools everywhere? C. Genevieve Wood, Vice President of Communicators at Family Research Council said, â€Å"What people really want is for their children to be taught an abstinence-centered education. By an almost 5 to 1 margin, parents approve or strongly approve of character-based, abstinence sex education. † What Wood is saying is that a staggering 5-1 ratio of parents approve of sex education. This also brought back my question, if it’s that one-sided, and it clearly seems to be a one-sided argument by this information, then why aren’t we teaching it everywhere? II. Some experts argue that sex education shouldn’t be taught in school. A. Robert Welch, the founder of The John Birch Society (an American radical-right wing political advocacy group that supports anti-communism, limited government, Americentrism and personal freedom) decided that sex education is a â€Å"filthy Communist plot. † B. According to the article Carnal Knowledge: The Sex Ed Debate, A Florida mother named Jodi Hoffman sued the Broward County Public Schools, claiming that their sex education classes were too explicit. She believes that sex education should only be taught at home, never in schools, in order to teach children the values the parents want to instill in them. Also, she spoke of the religious aspect. The school’s program clashed with her family’s religious beliefs. Hoffman said waiting until marriage to have sex â€Å"is the way God intended it to be. That’s how it’s taught in the Bible and those rules were not written for no reason. † C. In the essay Sex Education Should Be Taught By Parents, Not Schools by Eric Badertscher and Denise Grier, they claim that â€Å"school programs are said to treat the concept of sex as purely biological, without taking into consideration its mental, spiritual, emotional and social aspects. † What they’re saying is that when sex education is taught in school, the school only teaches the science of sex. They don’t let students know there’s other aspects to sex besides science such as emotions and mental aspects. They don’t teach students how to deal with their feelings about it, and at home that would happen. Conclusion: Think back to when you were in elementary, middle, and high school. Were you taught a form of sex education at school? And if so, did your parents agree with it? Now, if you have kids or plan to have kids, which way will you prefer for them to learn about sex? I’m sure there’s divided opinions among us, so who’s to say which way is right?

Saturday, October 19, 2019

Business accounting and the finance Pearson

This report has been prepared on an Australian pany which name is TPG Tel limited. This pany is working under the IT industry and the Australian tel munication industry. The main services of the pany are mobile telephone services and the internet services. According to a report, TPG tel is the second largest apny in Australian market in internet service provider panies. This pany is mainly a merger between total peripherals group. This pany has been founded in 1992 by Vickey Teoh and David. Basically, this pany is performing well in terms of finance as well as in terms of finance (About us, 2018). Ownership corporate governance of the TPG tel expresses about the way good structure of the investors. 82.74% stock of the pany own by the top 20 shareholders. The largest shareholder of the pany is WASHINGTON H SOUL PATTINSON AND PANY LIMITED. The pany has held 25.15% stock of the pany. Currently, there are 6 stockholders in the pany who has more than 5% stock in the pany’s shares and only 1 stockholder has more than 20% stock. Further, the annual report describe the CEO, executive directors, non executive directors, CFO etc of the pany has been evaluated and David Teoh is the executive chairman of the pany, Denis Ladbury, Robert Millner, Joseph Pang and Shane Teoh is the non executive directors of the pany. The report of top 20 shareholders of the pany explains that no members of the pany have more than 2% stock of the pany (Annual Report, 2018). Performance ratios of the pany have been described below. Performance ratios explain about the positive changes, position and the performance of the pany. Following are some of the performance ratios of TPG Tel as follows: Return on assets of the pany explains that the performance of the pany is quite better. It explains that how much profit is earned by the pany in context with the total assets. Following is the calculations of return on assets of the pany: Return on equity of the pany explains that the performance of the pany is quite better. It explains that how much profit is earned by the pany in context with the total equity. Following is the calculations of return on equity of the pany: Net profit after tax/ ordinary equity Debt ratios of the pany explain about the position and the capital structure of the pany. The current capital structure of the pany is way better. It explains that how much total liabilities are held by the pany in context with the total liability. Following is the calculations of debt ratio of the pany: EBIT / TA * NPAT / EBIT * TA/ OE = NPAT / OE Total assets and total equity determine the ROA and ROE of the pany with the help of the Net profit after tax. If the total assets and the total equity of an organization changes than it directly makes an impact over the ROA and the ROE (Deegan, 2013).   The above calculations on the TPG tel ’s ROE and ROA have been evaluated and it has been found that the ROA and ROE of the pany is 10.59% and 28.57%. It explains that the return on equity is always greater than the return on assets due to the accounting principle which states that the assets are the total of liabilities and the equity. The study of stock price has been evaluated further and it has been analyzed that the stock price of the pany and the stock price of AORD, both are quite volatile in nature and explains about the good performance of the pany (Yahoo finance, 2018). The following graph explains about the stock prices of both the stocks: Further, the graph epxlains that the correlation of the pany is in negative as it explains about the negative relationship among both the stocks. It epxlains that the changes in the stock of TPG is quite higher than the volatility of AORD stocks. Further, it explains that currently the stock price of the pany is way better (Brown, Beekes and Verhoeven, 2011).   Further, the factors has been evalauted which have imapcted on the stock price and due to which the stock of the pany has been changed. The main reason behind chnage is the petetion level of the pany, current report about the pany that is the second largest pany in the industry, further, the analysts has   described in their report about a better position of the pany in the market (Davies and Crawford, 2011). On the other hand, due to new technology and patetion the stock price of the pany has been lowered 2 to 3 times. The calculation on the stock price of the pany depicts that the beta of the pany is 0.7415. The required rate of return of the pany is as follows: Calculation of cost of equity (CAPM) The above calculations express that the pany’s cost in terms of equity is 5.48%. If the pany wants to raises the funds through equity than the pany has to pay 5.48% of total profit as cost of equity to the stockholders of the pany. The cost of equity of the pany is moderate.   According to the evaluation, it has been found that the risk of the pany is lower and return of the pany is quite higher and thus the pany is a conservative investment. Calculations of WACC are as follows: Calculation of cost of equity (CAPM) The above calculations express that the pany’s cost in terms of equity is 5.48% and in terms of debt is 4.2%. If the pany wants to raises the funds through equity than the pany has to pay 5.48% of total profit as cost of equity to the stockholders of the pany. On the other hand, in terms of debt, pany has to pay 4.2%. The cost of equity of the pany is higher than the cost of debt of the pany. The above calculations express that the cost of capital of the pany is 4.07%. Optimal capital structure of the pany explains that the liabilities of the pany have been reduced by the pany to manage a better capital structure. (Brown, Beekes and Verhoeven, 2011) Gearing ratios of the pany explains about the liabilities of the pany which has been reduced and the borrowings of the pany has been increased in current month and thus the gearing ratios of the pany has been lowered. Total Liabilities/ Capital employed Total Liabilities/ Capital employed The annual report of the pany expresses that the pany offers a great dividend to the pany with a 1.25% growth rate each year. It depicts that the pany is following relevant dividend policies (Annual report, 2018). Relevant dividend policies are a part of dividend policies. These policies explain to the pany that they should announce and give a good amount of dividend to the stockholder so that the investment level of the pany could be enhanced. Subject: R mendation about investment. It is r mended to you to invest into TPG tel . The report of evaluation of TPG tel briefs that the current position of the pany is quite attractive. It presents that the huge profit is earned by the pany and the great amount of dividend is given to the shareholders of the pany. The market stock price of the pany is also good. It explains that the investors should invest into the pany.   So, it is the best option for you to invest right now. About us. 2018. TPG Tel Limited. viewed Jan 25, 2018, https://www.tpg .au/ Annual Report. 2018. TPG Tel Limited. viewed Jan 25, 2018, https://www.tpg .au/about/pdfs/FY17%20Annual%20Report.pdf Brown, P., Beekes, W., and Verhoeven, P. 2011. Corporate governance, accounting and finance: A review.  Accounting & finance,  51(1), 96-172. Davies, T. and Crawford, I., 2011. Business accounting and finance. Pearson. Davies, T. and Crawford, I., 2011.  Business accounting and finance. Pearson. Deegan, C., 2013. Financial accounting theory. McGraw-Hill Education Australia. Jiashu, G. 2009. Study on Fair Value Accounting——on the essential characteristics of financial accounting [J].  Accounting Research,  5, 003. Morningstar. 2018. TPG Tel Limited. viewed Jan 25, 2018, https://financials.morningstar /cash-flow/cf.html?t=XBER:YST®ion=deu&culture=en-US Yahoo Finance. 2018. TPG Tel Limited. viewed Jan 25, 2018, https://au.finance.yahoo /quote/TPM.AX/chart?p=TPM.AX

Friday, October 18, 2019

In the event of peace, and a Palestinian state being formed, Palestine Essay

In the event of peace, and a Palestinian state being formed, Palestine would suffer massive economic repercussions due to lack of competitiveness and underdevel - Essay Example The current economic scenario in Palestine is not very encouraging. In the second quarter of 2007, the GDP of Palestine grew by 6.5%. The largest increases in gross value added were registered the following sectors: education (+32.1%), hotels (+24.9%), health ( +15.2%), construction (+13.9%) and agriculture (+12.8%). There was a decline however in sectors like mining, water and electricity and manufacturing. However in Gaza, due to political problems, 95% of the factories in Gaza had closed down leading to 32000 job losses. Many of these factories were approaching a point of 'no return' where owners were likely to sell their assets and shut down completely. (The Portland trust, Nov, 2007) In the previous years, between 2005 and 2006, the GDP in Palestine fell by 8.8%. In the first quarter of 2007, the GDP fell by 4.2%. This was 13.2% lower than the GDP for the first quarter of 2006.(The Portland Trust, July 2007) Besides the negative growth of the economy, it is the composition of the GDP that remains a cause for concern. The GDP is driven by Government and private consumption from aid rather than investment or production. Public sector employment for instance has increased by 60% between 1999 and 2006. Much of the foreign aid which could e used in infrastructure building is spent on salaries of government employees. (World Bank, 2007) Fig:2 Source: (World Bank Document, 2007) Even among Palestinians, the condition of those living in Gaza is particularly bad. Despite receiving aid, the number of people in Gaza living below the poverty line has increased from 21.6% in 1998 to nearly 35% in 2006. Without aid, the figure is likely to be around 67%. (World Bank, 2007) Fig:3 Source: (World Bank Document, 2007) Given the current economic scenario, it is likely that an independent Palestine face the immense challenge of managing the repercussions of years of negative economic growth and political instability. In the context of Palestine, the concept of 'peace' is crucial to the economy. According to a World Bank report, in 1968, an average Israeli was approximately 10 times richer than the average Palestinian. Today the situation is far worse. The GDP of Israel is almost 20 times that of Palestine and over 2/3rds of Palestinians live below the poverty line. (2007). This disparity in income level and lifestyle is a cause for concern. As Moshe Alamaro, a research scientist at the University of Massachusetts points out there can be no lasting peace if a destitute third world nation stress across the border to find a prosperous modern democracy. Alamaro compares the relationship between Japan and North Korea to that between in Israel and Palestine and says that Japan helped fuel economic growth in South Korea and thereby avoid any friction between the two states. Similarly, he believes that the west along with Israel needs to fuel economic growth in Palestine and thereby establish a mutually beneficial socio-economic relationship.(Alamaro, 2002) From the Palestinian perspective however, it is important to break free from the dependence on Israel. The Palestine National authority has charted a framework for Economic development. The framework suggests that dependence on Israel can be reduced by diversifying the export markets and

Evidence based practice Essay Example | Topics and Well Written Essays - 2000 words - 3

Evidence based practice - Essay Example A careful review of the available literature exposes some of the difficulties discovered in finding an answer to this question. Intake of omega n-3 (VLCn3 PUFAs) could be associated to construction and functional development of cognitive, sensory, perceptual, and motor neural systems. Docosahexaenoic acid (DHA), an omega n-3, is crucial for the growth and functional development of the brain in infants. DHA is also required for preservation of the normal brain function in adults. The addition of rich DHA in the diet can improve the individual’s learning capability, while insufficient DHA is linked with insufficiency in learning. DHA is drawn into the brain in preference to other fatty acids and the speed at which DHA is assimilated in the brain is exceptionally fast, therefore requiring constant replenishment. In addition, the visual perception of healthy, full-term, formula-fed infants is amplified when their formula contains DHA. Throughout the last 50 years, infants have been given formula diets that are deficient in DHA and other omega-3 fatty acids. DHA deficiencies are associated with foetal alco hol syndrome, attention deficit hyperactivity disorder, cystic fibrosis, phenylketonuria, unipolar depression, aggressive hostility, and adrenoleukodystrophy. Low levels of DHA in the brain are connected with cognitive decline during aging and with onset of sporadic Alzheimer disease (Martinez 1996). Reports have been generated over the last few years, regarding supplements of omega n-3 fish oil, and the effects that it may have on children of school age to improve their behaviour, mental capacity and studying performance amid concerns of poor diet amongst the younger generation (Poulter, 2006). This subject has evoked a lot of interest in the media from ministers to health care professionals, parents and school authorities (Poulter 2006). The vast amount of research by the scientific community is still argumentative as to whether chemical pollution

Persuasive Presentation Essay Example | Topics and Well Written Essays - 500 words - 2

Persuasive Presentation - Essay Example How many of you feel that guns are necessary and imperative for self-protection? How would you feel if you knew how many people die of the gun each day? Our society has socialized as to acknowledge guns as a beautiful and powerful device but never mention how many people lose their life through it. The magazine, videos, and the internet depict gun ownership as a prestigious phenomenon without informing us on how many people died from gun-related incidences either as innocent or guilty victims. Unfortunately, most gun owners kill their loved ones including their partners and children. Having easy access to guns increases the risks of and opportunity for fatal violence. When individual without a stable emotions or tempers owns guns, the likelihood of involvement in violence is high when they are provoked. Imagine a violent father who regularly beats his wife and threatens to kill her has a gun at such a time of great emotion. Do you think he would hesitate to pull the trigger? Such a scenario might seem to be strange in the ‘civilized America where wife beating is presumed to be a retrogressive practice. Unfortunately, a few months ago, a friend of my uncle shot his wife because of a simple domestic argument. Regrettably, he realised that he had killed his wife when it was too late. Another instance occurred in a public Restaurant where a waiter provoked a drunken man, and he removed his handgun and shot her in the chest; she died instantly. Guns are a risk to the owner and children in the family. According to the Childrens Defence Fund and National Center for Statistics, approximately eight children die each day, and about fifty die every week due to gunfire. Additionally, five times as many children and teenagers suffer fatal injuries related to firearms. It is not once that the media has reported a juvenile death related to improper handling of the

Thursday, October 17, 2019

Transplant Coursework Example | Topics and Well Written Essays - 250 words

Transplant - Coursework Example The disadvantage is that it causes people to think about donating organs without inherently wanting so. Also, ‘Youre also giving up your right to informed consent. Doctors dont have to tell you or your relatives what they will do to your body during an organ harvest operation because youll be dead, with no legal rights† (Teresi, 2012). The main factor that causes this discrepancy is the unwillingness to donate the organ in the relatives. Each year, at least 5000 medically transplantable organs are refused donation by the relatives in the US (Reeves et al., 2004). Other factors may include diseased or infections organs in the donors, and religious and cultural stance on donation. A professional nurse plays a very important role of advocate and educator in organ donation. Professional nurses facilitate organ donation process by convincing the donors and their relatives of the safety of operation. Their role as psychological counselors of the donors and their relatives is also very

Infection Control Essay Example | Topics and Well Written Essays - 1000 words

Infection Control - Essay Example We shall now talk about an infection that takes place during the course of medical treatment itself. Aids, the global scare made many medical professionals to use sterilized needles during their process of treatment. The single-puncture syringe that cannot puncture the skin once it is used is the best form of administering equipment for anesthetic and other medications. The profession is to go miles before attaining complete protective treatment. One of the most dreads that now posed by the ultrasound treatment is the use of gels. When an object or human body part is exposed to ultrasonic waves, density differences inside the object or the body parts cause some waves to reflect at the point of interface. This reflection is built into an image of the internal part of the body and its structure on the monitor screen. A gel or jelly is normally used to transmit the acoustic waves through the transducers—a device that contains a crystal, which converts alternating electric current s into vibrations—to the object or the internal part of the body.Experiments show that a high-energy ultra sound emitter inserted through an angioplasty catheter can effectively break up the blocks and restore normal blood circulation. In many patients, bacteremia is a result of an intravascular focus, such as a contaminated catheter or prosthetic device.Contamination of the gel at the manufacturing facility and improper use of the gel at clinical settings are the sources of many cases of bacteremia and septicemia.aemia. Non-sterile gels meant for external use, when used for invasive procedures like biopsies, put most of the patients under the risk of infection. Some precautionary measures can be followed to reduce the risk of infection. Separate individual procedures for sterile and non-sterile gels are postulated by Canadian Health Authorities. They are: - Sterile gels: - 1. Sterile gels must be used for all invasive procedures especially on babies in neonatal I C U. 2. Bacteriostatic gels should be considered for intact mucous membrane operations like oesophagal, rectal and vaginal areas. 3. Sterile packages must be used for one time use only. Non-sterile gels: - 1. Single use containers are the best for non-sterile gels. 2. In the situations of the use of reusable containers, the containers must invariably be cleaned thoroughly by using hospital-grade disinfectants. The very

Wednesday, October 16, 2019

Persuasive Presentation Essay Example | Topics and Well Written Essays - 500 words - 2

Persuasive Presentation - Essay Example How many of you feel that guns are necessary and imperative for self-protection? How would you feel if you knew how many people die of the gun each day? Our society has socialized as to acknowledge guns as a beautiful and powerful device but never mention how many people lose their life through it. The magazine, videos, and the internet depict gun ownership as a prestigious phenomenon without informing us on how many people died from gun-related incidences either as innocent or guilty victims. Unfortunately, most gun owners kill their loved ones including their partners and children. Having easy access to guns increases the risks of and opportunity for fatal violence. When individual without a stable emotions or tempers owns guns, the likelihood of involvement in violence is high when they are provoked. Imagine a violent father who regularly beats his wife and threatens to kill her has a gun at such a time of great emotion. Do you think he would hesitate to pull the trigger? Such a scenario might seem to be strange in the ‘civilized America where wife beating is presumed to be a retrogressive practice. Unfortunately, a few months ago, a friend of my uncle shot his wife because of a simple domestic argument. Regrettably, he realised that he had killed his wife when it was too late. Another instance occurred in a public Restaurant where a waiter provoked a drunken man, and he removed his handgun and shot her in the chest; she died instantly. Guns are a risk to the owner and children in the family. According to the Childrens Defence Fund and National Center for Statistics, approximately eight children die each day, and about fifty die every week due to gunfire. Additionally, five times as many children and teenagers suffer fatal injuries related to firearms. It is not once that the media has reported a juvenile death related to improper handling of the

Infection Control Essay Example | Topics and Well Written Essays - 1000 words

Infection Control - Essay Example We shall now talk about an infection that takes place during the course of medical treatment itself. Aids, the global scare made many medical professionals to use sterilized needles during their process of treatment. The single-puncture syringe that cannot puncture the skin once it is used is the best form of administering equipment for anesthetic and other medications. The profession is to go miles before attaining complete protective treatment. One of the most dreads that now posed by the ultrasound treatment is the use of gels. When an object or human body part is exposed to ultrasonic waves, density differences inside the object or the body parts cause some waves to reflect at the point of interface. This reflection is built into an image of the internal part of the body and its structure on the monitor screen. A gel or jelly is normally used to transmit the acoustic waves through the transducers—a device that contains a crystal, which converts alternating electric current s into vibrations—to the object or the internal part of the body.Experiments show that a high-energy ultra sound emitter inserted through an angioplasty catheter can effectively break up the blocks and restore normal blood circulation. In many patients, bacteremia is a result of an intravascular focus, such as a contaminated catheter or prosthetic device.Contamination of the gel at the manufacturing facility and improper use of the gel at clinical settings are the sources of many cases of bacteremia and septicemia.aemia. Non-sterile gels meant for external use, when used for invasive procedures like biopsies, put most of the patients under the risk of infection. Some precautionary measures can be followed to reduce the risk of infection. Separate individual procedures for sterile and non-sterile gels are postulated by Canadian Health Authorities. They are: - Sterile gels: - 1. Sterile gels must be used for all invasive procedures especially on babies in neonatal I C U. 2. Bacteriostatic gels should be considered for intact mucous membrane operations like oesophagal, rectal and vaginal areas. 3. Sterile packages must be used for one time use only. Non-sterile gels: - 1. Single use containers are the best for non-sterile gels. 2. In the situations of the use of reusable containers, the containers must invariably be cleaned thoroughly by using hospital-grade disinfectants. The very

Tuesday, October 15, 2019

A Probe into Literary Symbolism Essay Example for Free

A Probe into Literary Symbolism Essay â€Å"â€Å"This here is my name, to begin with,† he said. ARNOLD FRIEND was written in tarlike black letters on the side†¦Ã¢â‚¬  (Oates, 33). This self-introduction of Arnold Friend in Joyce Carol Oates’ Where Are You Going, Where Have You Been? sums up the allegorical irony which is also to be found in Good Country People by Flannery O’Connor. Both the short stories are replete with a profusion of symbolisms acting as a set of literary devices. This essay is going to probe into literary symbolisms and their influence on the overall development of the two short stories. Especial emphasis will be given to two symbolic literary devices that have helped establish the thematic constructs. Three main themes are addressed in Good Country People: good versus evil; the likelihood of salvation after experience with violence and the exposing of intellectual falsifications. (enotes, 2009) The protagonist Joy, who later changes her name to Hulga, becomes aware of the evil through her bitter encounter with Manley Pointer, a Bible salesman. Even though she used to take pride in her being different from other country people courtesy of education, it occurs to her in the course of her life that ‘Nothing’ is the only substantial faith she can cling onto. So the knowledge of evil she gains can be attributed to her experience with nothingness. This hefty irony is masterfully explained through the symbolic usage of character names. The plot lacks in motion as far as external flow of action is concerned. Instead, the author concentrates on the internal world of her characters to study their psychological traits. Born as Joy, the protagonist changes her name to Hulga because she thinks she is too ugly to be called by a happy name such as Joy. She deliberately misleads her family in order to find peace in isolation. Her mother Mrs. Hopewell’s name bears another striking irony in the sense that their family, once struck with misery and economic struggle, is stripped off both hope and wellness. Mr. and Mrs. Freeman belong to the social status of tenant farmers and hence they are not free. But the most subtle irony is demonstrated in the naming of the Bible salesman Manley Pointer. There is a phallic allusion to the first name, suggestive of a male dominance. (Associated Content, 2007) In addition to this, his subsequent escapades with Hulga are hardly in sync with the profession he is in. Inspired by the infamous Tucson killing of several girls by a young man in the early 1960s, Joyce Carol Oats wrote the short story Where Are You Going, Where Have You Been? which was published in her short story collection The Wheel of Love in 1970. From thematic perspectives, the story fundamentally deals with teenage problems of sensible perspectives. Connie, a typical teenage uptown girl, is preoccupied with material thoughts and concerns. Her actions are grossly impulsive without much forethought into consequences. Connie’s flirtatious demeanor lands her in serious trouble once she comes in contact with Arnold Friend. So the story can be regarded as a contemporary documentation of the American society in the 1960s and 1970s, highlighting the adolescent perils. As far as literary device is concerned, the character of Arnold Friend is thematically antonymous to his name. His manipulative use of language exerts psychological pressures on Connie. Friend’s strange physical appearance makes for the unique interpretation that he is a manifestation of the devil: â€Å"One of his boots was at a strange angle, as if his foot wasnt in it. It pointed out to the left, bent at the ankle. † (Celestial Timepiece, 2007) Furthermore, the referral to the possibility of Friend’s wooden leg can be compared with Hulga’s wooden leg in Good Country People. Now as Hulga undergoes a transformation of sorts in the end of the story, Oats keeps her readers guessing about the fate of Connie. There is ample evidence to suggest that just like Hulga, Connie also heads for a bleak destiny after she confronts devil in the form of Friend. This subtle but expressive use of symbolism accounts for a potent literary device in both the short stories. A thorough character analysis of the two protagonists leads to the finding of more resemblances than differences. Both have been given their fair share of intellectual sophistication in the beginning before the thematic construct of isolation is built around them. Hulga’s didactic but hollow conversation with Manley only reveals her intense urge to be seen by others as socially superior. Similarly, Connie’s careless disposition in the way she wishes to draw the attention of older high school boys is just too pretentious to pass for honest and sensible behavior. Although Where Are You Going, Where Have You Been? has significantly lesser number of characters compared to Good Country People, it is evident from the reading that the fate of nearly all the characters in both stories hinges on the actions of the main protagonists. If this minimalist factor, particularly in case of the second story, is taken into consideration as a parameter for symbolic interpretation of the texts, both authors leave plenty of scope for the readers to assess the thematic progressions. Bibliography Associated Content. (2007, May 7). An Analysis of Flannery O’Connor’s Good Country People.Retrieved March 12, 2009, from http://www. associatedcontent. com/article/235649/an_analysis_of_flannery_oconnors_good_pg2. html? cat=4 Celestial Timepiece. (2007). Where Are You Going, Where Have You Been?. Retrieved March 12, 2009, from http://jco. usfca. edu/works/wgoing/text. html enotes. (2009). Good Country People Overview. Retrieved March 12, 2009, from http://www. enotes. com/good-country-people Oates, Joyce Carol. , and Showalter, Elaine. â€Å"Where are you going, where have you been? †. Piscataway: Rutgers University Press, 1994.

Monday, October 14, 2019

UK Cheese Market Analysis

UK Cheese Market Analysis Assignment about The Cheese and its Determining Factors on the Market Executive Summary Economy in the real world is not just a subject in the university, but the major basic of a modern day business. â€Å"The large set of inter-related economic production and consumption activities which aid in determining how scarce resources are allocated.† (Investopedia.com, 2014) The report describes the cheese market in the United Kingdom. Highlight the relationship between wine and its compliment, the cheese and how the actual market responsive to economical changes, such as demand, supply, elasticity and equilibrium. Table of Contents Introduction.4 Main Body5 1.The aspects which influencing the amount of cheese..5 2. About Elasticity and Inelastic6 3. About Equilibrium.7 4. Example for the cheese` prise changing..8 5. Recently used marketing strategy..9 Conclusion..10 Bibliography.11 Introduction This report created by the Author –Mr. Istvan Csuha– on the request of Northampton University on the behalf of its subsidiary the London School of Business and Management and their lecturers in respect Prof. Bruce Johnson to clarify the position of the cheese market in the United Kingdom, the key economic factors which influences marketers and consumers in the decision making process. Main Body The aspects which influencing the amount of cheese The aspects influencing the amount of cheese that shoppers request can be categorised four main parts (Begg, D. & Ward, D., 2007, P.26-32), such as: Costs of surrogates: relates to researches (Fitday.com. 2013). there are some options to alternate cheese, but the prices of those merchandises is higher and do not give back the same taste, as cheese, therefore only a small amount of clients will leave â€Å"the cheesy side†. Salary of the clients: an investment banker demand is completely different, then a street cleaner and one of the key motivator is what they can afford; ASDA have been closely monitored and the finding is, individuals can purchase cheese products from  £2 up to  £20, therefore cheese products widely accessible to everyone (ASDA.com. 2014). Various flavours: Every single human being different from the other, so as their tastes and conclusion of that, they required different products. Value: is the product worth the sum of money what the retailer asking for it; if the answer is yes, then highly possible the quantity demanded by a consumer is higher. About Elasticity and Inelastic The characteristics of the magnitude of cheese that manufacturers and retailers supply is strongly related to the previous part of the report, but a new economic term has to be considered, Elasticity: â€Å"Price elasticity of supply measures the relationship between change in quantity supplied and a change in price.† (Tutor2u.net. 2014). There are Inelastic is the modification in the price indicates a proportionately minor modification in the quantity required. (Begg, D. & Ward, D. 2007, P.35) Elastic is the modification in the price indicates considerable larger modification in demand. (ibid, P. 32-35) There is another very important factor what every supplier have to consider regarding the amounts need to supply and is called a well-known PESTEL analysis -macro-environmental aspects, what a supplier cannot change, only can adapt to them. Assuming there are alterations in the purchasers â€Å"tongs†: Consumer demand decreasing= retailer profit decreasing also. Overcome on that retailers has to start manufacturing products, therefore they have to enter a new segment of the market. Avoid failure Porters five forces advisable to considered, -designed to evaluate the possibilities of the company upon entering to a new market and/or segment. Assuming there are modifications in the manufacturers technology, -that is a technological factor from the mentioned PESTEL analysis-: In that occasion the retailer or the consumer only can adapt to that factor, in that case keep purchasing products, but less quantity (if the technology is not as cost-effective anymore, therefore the price of the product rising too), or find a substitute (either retailer or substitute product). Therefore price elasticity applied. About Equilibrium Equilibrium of â€Å"cheese market wise†, when the manufacturer selling the product for the price, what a retailer is demanded, or the distributor selling the merchandise for the price, what a consumer demanded. (ibid, P.76) According to worldwide known economists and authors of many books the forces that drive the market in the direction of its equilibrium are: The connection between the alteration of need and supply and prices: if the need of cheese products rising, supply has to follow, then retailers raise their prices too, therefore the equilibrium will balanced again. Need for cheeses falling, then traders have to reduce their activity, therefore prices will fall too. That is the optimal market scenario. (ibid, P.88) Example for the cheese` prise changing Assumption: a hypothetical situation, when the price of wine increases. First we have to clarify the right questions. The author of these report was that fortunate, came from the family which have long-lasting history –and himself spent over ten years as well- in the Hospitality and Catering Industry; worked from kitchen porter through sommelier assistant to night manager in various countries and several high-end catering event as well (for example: wine-waiter at the House of Parliament in Hungary), therefore to clarify and answer this questions was his table. Why wine and cheese related to each other? How the supply of wine and cheese will change? How the needs of wine and cheese will change? Will the prices of cheese change? Are the amount of cheese and wine supplied and demanded will change? The answers are the following: Many countries –especially the ones with long-lasting histories and more mature cuisine i.e.: France and the United Kingdom- use cheese, as a substitute of desserts, also another reason possibly, because the weather colder than for example Italy and Spain. Those countries, consuming mostly wine for/and throughout the meal, if their choice for the dessert is any sweet, -such as ice cream or crà ¨me bulee-, they choose a light and sweet liquor, or a dessert-wine; but when they choose cheese, then the wine has to be semi-dry, or dry light white-wine. When the price of wine increasing, in the short term the supply will be the same, until marketer realise the equilibrium turned into a disequilibrium –at this occasion the proper term is surplus, when the supply of goods greater than its demands-, and they want to balance again; therefore marketers reducing supplies. The needs of cheese and wine at the event of the price of the wine increase can be: The increase of the price will be minor, therefore only small amount of purchaser decide to discontinue consuming those products, therefore inelasticity occur. When the needs of cheese and wine reactive to the price change, then â€Å"massive† amount of purchasers decide to discontinue purchasing products= elasticity occurs. The price of the cheese can be reactive to the wine price (elastic), or non-reactive (inelastic). When: The quantity of demand reactive to the price change: yes= elasticity; The amount of need non-reactive: no= inelasticity; Marketers want to balance the equilibrium, yes, when the demand decreases, the quantity of supply has to follow, therefore the price will change to; when equilibrium reached, demand is increasing, supply increasing, prices increasing. 5. Recently used marketing strategy Companies nowadays like to use a new marketing strategy. Organisations evaluate the demand and the quantity of demand, they producing less quantity of product, therefore artificially create shortage and they can raise the prices too, i.e.: entry-tickets for pop-concerts. (ibid, P.85-86) Conclusion The report found the cheese market very responsive for price changes, which is depending on various factors. Found also the definition of economy; clearly concluded the meaning / variations of elasticity, moreover described the definition of equilibrium. Bibliography ASDA.com. (2014). Asda Groceries. Available: http://groceries.asda.com/asda-webstore/landing/home.shtml?cmpid=ahc-_-ghs-sna1-_-asdacom-dsk-_-hp#search/cheese/7/price_asc. Last accessed 11.12.2014. Begg, D. & Ward, D. (2007). Economics for Business. 2nd ed. New York: McGraw-Hill. p26-p32. Begg, D. & Ward, D. (2007). Economics for Business. 2nd ed. New York: McGraw-Hill. p32-p35. Begg, D. & Ward, D. (2007). Economics for Business. 2nd ed. New York: McGraw-Hill. p76. Begg, D. & Ward, D. (2007). Economics for Business. 2nd ed. New York: McGraw-Hill.p85-86. Begg, D. & Ward, D. (2007). Economics for Business. 2nd ed. New York: McGraw-Hill. p88. Fitday.com. (2013). Substitutions for Cheese. Available: http://www.fitday.com/fitness-articles/nutrition/healthy-eating/substitutions-for-cheese.html. Last accessed 11.12.2014. Investopedia.com. (2014). Definition of Economy. Available: http://www.investopedia.com/terms/e/economy.asp. Last accessed 11.12.2014. Tutor2u.net. (2014). Elasticity of Supply. Available: http://www.tutor2u.net/economics/content/topics/elasticity/elasticity_of_supply.htm. Last accessed 11.12.2014. LON 15403546Mr. Istvà ¡n Csuha